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COPS2 / TRIP15 / ALIEN

COP9 signalosome subunit 2

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Gene Name: COP9 signalosome subunit 2
Synonyms: COPS2, Alien homolog, ALIEN, SGN2, TRIP15, TR-interacting protein 15, Signalosome subunit 2, TRIP-15
Target Sequences: NM_004236 NP_004227.1 P61201

☰ Filters
Products
Antibodies (44)
Primary (44)
COPS2 / TRIP15 / ALIEN (44)
Human (44)
Mouse (29)
Rat (26)
Bat (13)
Bovine (13)
Chicken (13)
Chimpanzee (12)
Dog (13)
Drosophila (7)
Gibbon (12)
Guinea pig (12)
Horse (13)
Monkey (14)
Pig (13)
Rabbit (13)
Xenopus (13)
Zebrafish (12)
IHC (20)
IHC-P (11)
WB (42)
ELISA (17)
ICC (1)
IF (8)
IP (1)
Peptide-ELISA (4)
rabbit (37)
mouse (6)
goat (1)
Product Group
IHCPlus (3)
IgG (35)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (38)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (22)
N-Terminus (16)
aa1-30 (6)
aa1-310 (2)
aa1-50 (2)
150-230 aa, Internal (1)
aa158-207 (1)
aa181-230 (1)
aa344-443 (1)
aa439-451 (1)
No (44)
COPS2 / TRIP15 / ALIEN Antibody - Anti-COPS2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
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COPS2 / TRIP15 / ALIEN Goat anti-Human Polyclonal (aa439-451) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
COPS2 / TRIP15 / ALIEN Antibody - COPS2 antibody COPS2(COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
COPS2 / TRIP15 / ALIEN Antibody - COPS2 antibody COPS2(COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
COPS2 / TRIP15 / ALIEN Antibody - COPS2 antibody COPS2(COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
COPS2 / TRIP15 / ALIEN Antibody - COPS2 antibody COPS2(COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
COPS2 / TRIP15 / ALIEN Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
COPS2 / TRIP15 / ALIEN Antibody
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (150-230 aa, Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
COPS2 / TRIP15 / ALIEN Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
COPS2 / TRIP15 / ALIEN Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-310) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
COPS2 / TRIP15 / ALIEN Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using COPS2 antibody.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
COPS2 / TRIP15 / ALIEN Antibody - Immunofluorescence analysis of A549 cells, using COPS2 Antibody. The picture on the right is blocked with the synthesized peptide.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa181-230) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
COPS2 / TRIP15 / ALIEN Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
Select
COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-310) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
COPS2 / TRIP15 / ALIEN Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
COPS2 / TRIP15 / ALIEN Mouse anti-Human Monoclonal (aa344-443) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$705
Select
COPS2 / TRIP15 / ALIEN Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Rat, Human
ELISA, WB
PE Conjugated
100 µl/$904
COPS2 / TRIP15 / ALIEN Antibody - Detection of Human CSN2 by Immunohistochemistry. Sample: FFPE section of human anaplastic thyroid carcinoma. Antibody: Affinity purified rabbit anti-CSN2 used at a dilution of 1:500.
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COPS2 / TRIP15 / ALIEN Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
1 µg/$295; 100 µl/$532
Viewing 1-25 of 44 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).