COPB1 / Beta-COP

coatomer protein complex, subunit beta 1

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Plays a functional role in facilitating the transport of kappa-type opioid receptor mRNAs into axons and enhances translation of these proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte surface triglyceride lipase (PNPLA2) with the lipid droplet to mediate lipolysis (By similarity). Involved in the Golgi disassembly and reassembly processes during cell cycle. Involved in autophagy by playing a role in early endosome function. Plays a role in organellar compartmentalization of secretory compartments including endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), Golgi, trans-Golgi network (TGN) and recycling endosomes, and in biosynthetic transport of CAV1. Promotes degradation of Nef cellular targets CD4 and MHC class I antigens by facilitating their trafficking to degradative compartments.

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Proteins (9)

Type

Over-Expression Lysate (6)

Recombinant (3)

Target

COPB1 / Beta-COP (9)

Publications

No (9)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (8)

Species

Human (6)

Source

293T Cells (3)

HEK 293 Cells (5)

Wheat Germ Extract (1)

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COPB1 / Beta-COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126322

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

100 µg/$710

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COPB1 / Beta-COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126326

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

100 µg/$710

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Human COPB1 / Beta-COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87489

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

20 µg/$215

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Human COPB1 / Beta-COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87490

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

20 µg/$215

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Human COPB1 / Beta-COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87491

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

20 µg/$150

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Human COPB1 / Beta-COP Protein (Recombinant GST, N-terminus) (aa854-953) - LS-G58181

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human COPB1 / Beta-COP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70575

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

20 µg/$1,107

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Human COPB1 / Beta-COP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70581

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

20 µg/$1,107

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COPB1 / Beta-COP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101438

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107 kDa

Price:

100 µg/$494

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