Complement C3a

Complement C3/C3a

C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue peptide that binds to the C3a receptor (C3aR) a class A G protein-coupled receptor. It stimulates mast cell degranulation, thus triggering an immune response. C3a plays an important role in chemotaxis, though not as important a role as C5a. It is also an anaphylatoxin and the precursor of the important cytokine (adipokine) ASP through its interaction with carboxypeptidase B. Because C3a is rapidly degraded in serum, stable small molecule agonists and antagonists may be used as tools to probe the physiological effects of C3a in vivo.

Complement C3a Target Details

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Proteins (4)

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Recombinant (4)

Target

Complement C3a (4)

Publications

No (4)

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His (1)

His-GST (3)

Species

Human (1)

Mouse (1)

Pig (1)

Rat (1)

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E. coli (4)

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Rat Complement C3a Protein (Recombinant His) (aa671-748) - LS-G12084

Source:

E. coli

Tag:

His

Molecular Weight:

40.3 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Mouse Complement C3a Protein (Recombinant His-GST) (aa671-748) - LS-G12082

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.2 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Pig Complement C3a Protein (Recombinant His-GST) (aa670-742) - LS-G12083

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.1 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Human Complement C3a Protein (Recombinant His-GST) (aa672-748) - LS-G12078

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.1 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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