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Unfortunately, the antibody (ID:426344) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



Complement C3

complement component 3

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Gene Name: complement component 3
Synonyms: C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3
Target Sequences: NM_000064 NP_000055.2 P01024

Publications (3)

1
Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia. Wang W, Irani RA, Zhang Y, Ramin SM, Blackwell SC, Tao L, Kellems RE, Xia Y. Hypertension. 2012 60:712-21. (IHC; Mouse) [Full Text Article] [PubMed:22868393] [PMC:PMC4131740] Related Antibodies: LS-C22283.
2
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites. Braig D, Nero TL, Koch HG, Kaiser B, Wang X, Thiele JR, Morton CJ, Zeller J, Kiefer J, Potempa LA, Mellett NA, Miles LA, Du XJ, Meikle PJ, Huber-Lang M, Stark GB, Parker MW, Peter K, Eisenhardt SU. Nature communications. 2017 8:14188. (Flo; Human) [Full Text Article] [PubMed:28112148] [PMC:PMC5264208] Related Antibodies: LS-C62856.
3
Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway-mediated diseases. Fridkis-Hareli M, Storek M, Mazsaroff I, Risitano AM, Lundberg AS, Horvath CJ, Holers VM. Blood. 2011 118:4705-13. (Flo; Human) [Full Text Article] [PubMed:21860027] Related Antibodies: LS-C34556.

Filtered By: None
Target
complement-c3 (137)
Reactivity
Human (94)
Mouse (18)
Rat (16)
Chicken (1)
Guinea pig (1)
Monkey (1)
Pig (11)
Rabbit (1)
Application
IHC (71)
IHC-Fr (13)
IHC-P (10)
WB (93)
Flo (22)
ELISA (73)
ICC (5)
ID (1)
IF (1)
IP (3)
Peptide-ELISA (2)
RIA (3)
Turbidimetry (3)
Host
rabbit (57)
mouse (61)
goat (13)
chicken (1)
rat (2)
sheep (3)
Isotype
IgG (62)
IgG1 (37)
IgG1,k (9)
IgG2a (3)
IgG2a,k (3)
IgG2b (5)
IgG2b,k (5)
Clonality
monoclonal mc (63)
polyclonal pc (74)
Clone
10A1 (1)
10C7 (4)
11H9 (1)
12E2 (2)
2D8 (2)
4C6A8 (1)
5F9 (1)
6C9 (4)
8B5H2 (1)
8G4 (1)
BH6 (1)
C3-9 (1)
F1-8 (1)
H11 (1)
H13 (2)
KT17 (2)
Format
AP Conjugated (4)
APC (4)
APC Conjugated (4)
Biotin Conjugated (13)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
Fab'2 (1)
FITC Conjugated (16)
HRP Conjugated (9)
PE Conjugated (9)
Unconjugated (74)
Epitope
aa1322-1661 (11)
aa23-300 (10)
aa1314-1663 (8)
aa966-1313 (8)
C-Terminus (1)
aa1580-1592 (1)
aa681-693 (1)
Publications
No (134)
Yes (3)
Showing 1-25 out of 137 results
Anti-Complement C3 Antibody (clone 2D8) IHC-plus™ LS-B2545
Anti-Complement C3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2545 concentration 10 ug/ml.

Mouse Monoclonal [clone 2D8] (IgG1,k) to Human Complement C3
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-Complement C3 Antibody (clone 11H9) LS-C22283

Rat Monoclonal [clone 11H9] (IgG2a) to Mouse Complement C3
Mouse
ELISA Flo IHC IHC-Fr IP WB
Unconjugated
Anti-Complement C3 Antibody (clone 5F9) IHC-plus™ LS-B4290
Anti-Complement C3 antibody IHC of human vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4290 concentration 5 ug/ml.
C3 monoclonal antibody, clone 5F9 Western blot of C3 expression in A-431.

Mouse Monoclonal [clone 5F9] (IgG2a,k) to Human Complement C3
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-Complement C3 Antibody (clone 6C9) LS-C34556

Mouse Monoclonal [clone 6C9] (IgG1) to Human Complement C3
Human
ELISA Flo
Unconjugated
Anti-Complement C3 Antibody (clone 6C9, PE) LS-C62856

Mouse Monoclonal [clone 6C9] (IgG1) to Human Complement C3
Human
ELISA Flo
PE Conjugated
Anti-Complement C3 Antibody (clone 6C9, Biotin) LS-C62849

Mouse Monoclonal [clone 6C9] (IgG1) to Human Complement C3
Human
ELISA Flo
Biotin Conjugated
Anti-Complement C3 Antibody (clone 10C7, Biotin) LS-C62857

Mouse Monoclonal [clone 10C7] (IgG1) to Human Complement C3
Human
ELISA Flo
Biotin Conjugated
Anti-Complement C3 Antibody (clone 10C7, PE) LS-C62859

Mouse Monoclonal [clone 10C7] (IgG1) to Human Complement C3
Human
ELISA Flo
PE Conjugated
Anti-Complement C3 Antibody (clone 6C9, FITC) LS-C62855
Mouse thymocytes incubated with Rabbit Anti-Mouse T cells, then incubated with fresh human serum and stained with LS-C62855. Antibody concentration: 0.5ug/10^6 cells.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Mouse Monoclonal [clone 6C9] (IgG1) to Human Complement C3
Mouse, Human
ELISA Flo
FITC Conjugated
Anti-Complement C3 Antibody (clone 10C7, FITC) LS-C62858

Mouse Monoclonal [clone 10C7] (IgG1) to Human Complement C3
Human
Flo
FITC Conjugated
Anti-Complement C3 Antibody (aa1580-1592) IHC-plus™ LS-B11161
Anti-Complement C3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11161 concentration 5 ug/ml.
Anti-Complement C3 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Goat Polyclonal to Human Complement C3
Human, Monkey
IHC IHC-P Peptide-ELISA
Unconjugated
Anti-Complement C3 Antibody LS-C22284

Rabbit Polyclonal (IgG) to Mouse Complement C3
Mouse
IHC IHC-Fr WB
Unconjugated
Anti-Complement C3 Antibody LS-C128281

Goat Polyclonal (IgG) to Mouse Complement C3
Mouse
ELISA WB
Unconjugated
Anti-Complement C3 Antibody (Fab'2, AP) LS-C86901

Goat Polyclonal to Human Complement C3
Human
AP Conjugated, Fab'2
Anti-Complement C3 Antibody LS-C128285

Goat Polyclonal (IgG) to Human Complement C3
Human
ELISA WB
Unconjugated
Anti-Complement C3 Antibody (FITC) LS-C89054

Sheep Polyclonal (IgG) to Human Complement C3
Human
ELISA IF
FITC Conjugated
Anti-Complement C3 Antibody LS-C44997

Mouse Monoclonal (IgG1) to Human Complement C3
Human
ELISA Flo IHC IHC-Fr
Unconjugated
Anti-Complement C3 Antibody (clone BH6) LS-C121657

Mouse Monoclonal [clone BH6] (IgG2a) to Human Complement C3
Human
ELISA IHC IHC-Fr IHC-P
Unconjugated
Anti-Complement C3 Antibody (Biotin) LS-C316708
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human Complement C3
Human
ELISA IHC IHC-P WB
Biotin Conjugated
Anti-Complement C3 Antibody (clone H13) LS-C22305

Mouse Monoclonal [clone H13] (IgG2b) to Human Complement C3
Rabbit, Guinea pig, Human
IHC IHC-Fr WB
Unconjugated
Anti-Complement C3 Antibody LS-C123302

Mouse Monoclonal (IgG1) to Human Complement C3
Human
IHC IHC-Fr WB
Unconjugated
Anti-Complement C3 Antibody (clone 10C7) LS-C34557

Mouse Monoclonal [clone 10C7] (IgG1) to Human Complement C3
Human
ELISA Flo
Unconjugated
Anti-Complement C3 Antibody (clone 4C6A8) LS-C682385
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using C3C mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using C3C mouse mAb with DAB staining.

Mouse Monoclonal [clone 4C6A8] (IgG1) to Human Complement C3
Human
ELISA Flo ICC IHC WB
Unconjugated
Anti-Complement C3 Antibody (aa1314-1663, FITC) LS-C301804
Western blot of recombinant Complement C3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Mouse Complement C3
Mouse
IHC WB
FITC Conjugated
Anti-Complement C3 Antibody (aa23-300) LS-C372631
Western blot of Complement C3 antibody.

Rabbit Polyclonal (IgG) to Pig Complement C3
Pig
IHC WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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