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Complement C1q

C1q is a 400kDa protein formed from 18 peptide chains in 3 subunits (C1QA, C1QB, and C1QC). Each 6 peptide subunit consists of a Y-shaped pair of triple peptide helices joined at the stem and ending in a globular non-helical head.

Complement C1q Target Details

Target Name:

Complement C1q

Publications (2)

GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension. Jacob K Sterling, Modupe O Adetunji, Samyuktha Guttha, Albert R Bargoud, Katherine E Uyhazi, Ahmara G Ross, Joshua L Dunaief, Qi N Cui. Cell reports. 2020 November;33:108271. [Full Text Article] [PubMed:33147455] [PMC:PMC7660987]

Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease. Francheska Delgado-Peraza, Carlos J Nogueras-Ortiz, Olga Volpert, Dong Liu, Edward J Goetzl , Mark P Mattson, Nigel H Greig, Erez Eitan, Dimitrios Kapogiannis. Cells. 2021 Apr;10:993. [Full Text Article] [PubMed:33922642] [PMC:PMC8146429]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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