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COL6A1 / Collagen VI Alpha 1

collagen, type VI, alpha 1

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.

Gene Name: collagen, type VI, alpha 1
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL6A1, Alpha 1 (VI) chain (61 AA), Collagen alpha-1(VI) chain, Collagen alpha 1(vi), OPLL, Collagen, type VI, alpha 1
Target Sequences: NM_001848 NP_001839.2 P12109

Publications (1)

1
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. Edwin K Jackson, Zaichuan Mi, Delbert G Gillespie, Dongmei Cheng, Stevan P Tofovic. Journal of the American Heart Association. 2021 March;10:e020088. [Full Text Article] [PubMed:33682436] [PMC:PMC8174220]

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
COL6A1 / Collagen VI Alpha 1 (8)
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GST, N-terminus (1)
His (4)
Myc-DDK (Flag) (3)
Human (4)
Mouse (3)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
COL6A1 / Collagen VI Alpha 1 Protein - Recombinant Collagen Type VI Alpha 1 By SDS-PAGE
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E. coli
His
22.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
COL6A1 / Collagen VI Alpha 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
108.53 kDa
100 µg/$494
COL6A1 / Collagen VI Alpha 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
108.53 kDa
20 µg/$150
COL6A1 / Collagen VI Alpha 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
COL6A1 / Collagen VI Alpha 1 Protein - Purified recombinant protein COL6A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
106.4 kDa
20 µg/$1,107
COL6A1 / Collagen VI Alpha 1 Protein - Recombinant Collagen Type VI Alpha 1 By SDS-PAGE
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E. coli
His
21.8 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Select
E. coli
His
21.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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E. coli
His
16.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).