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COL4A2 / Collagen IV Alpha2

collagen, type IV, alpha 2

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

Gene Name: collagen, type IV, alpha 2
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL4A2, Canstatin, Collagen alpha-2(IV) chain, Collagen, type IV, alpha 2, ICH, POREN2
Target Sequences: X05610 CAA29098.1 P08572

Publications (1)

1
Defining the Extracellular Matrix of Rhabdomyosarcoma. Xiaolei Lian, J Steffan Bond, Narendra Bharathy, Sergei P Boudko, Elena Pokidysheva, Jack F Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H Gultekin, Noah E Berlow, Charles Keller. Frontiers in oncology. 2021 March;11:601957. [Full Text Article] [PubMed:33708626] [PMC:PMC7942227] Related Antibodies: LS-C176967.

☰ Filters
Products
Antibodies (29)
Primary (29)
COL4A2 / Collagen IV Alpha2 (29)
Human (29)
Mouse (9)
Rat (2)
IHC (13)
IHC-P (4)
WB (26)
Flo (7)
ELISA (14)
IF (6)
Peptide-ELISA (2)
rabbit (29)
Product Group
IHCPlus (2)
IgG (17)
polyclonal pc (29)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (14)
aa1487-1703 (8)
aa156-186 (7)
120-200 aa, N-terminal (1)
N-Terminus (1)
Pro175 (1)
aa151-200 (1)
No (28)
Yes (1)
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
COL4A2 / Collagen IV Alpha2 Antibody - IHC of COL4A2 (P175) pAb in paraffin-embedded human colon carcinoma tissue.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (Pro175) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
COL4A2 / Collagen IV Alpha2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Collagen IV a2 antibody.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
COL4A2 / Collagen IV Alpha2 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
COL4A2 / Collagen IV Alpha2 Antibody - 1:100 staining human breast tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
COL4A2 / Collagen IV Alpha2 Antibody - Western blot of COL4A2 antibody
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (120-200 aa, N-terminal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
COL4A2 / Collagen IV Alpha2 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
COL4A2 / Collagen IV Alpha2 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using COL4A2 Antibody at dilution of 1:50
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa156-186) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$331
COL4A2 / Collagen IV Alpha2 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using COL4A2 Polyclonal Antibody at dilution of 1:70.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
COL4A2 / Collagen IV Alpha2 Antibody - Western blot of recombinant COL4A2 / Collagen IV.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa1487-1703) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
COL4A2 / Collagen IV Alpha2 Antibody - Western blot of recombinant COL4A2 / Collagen IV.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa1487-1703) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
COL4A2 / Collagen IV Alpha2 Antibody - Western blot of recombinant COL4A2 / Collagen IV.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa1487-1703) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
COL4A2 / Collagen IV Alpha2 Antibody - Western blot of recombinant COL4A2 / Collagen IV.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa1487-1703) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
COL4A2 / Collagen IV Alpha2 Antibody - Western blot of recombinant COL4A2 / Collagen IV.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal (aa1487-1703) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
COL4A2 / Collagen IV Alpha2 Antibody - Western blot analysis of extracts of various cells.
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COL4A2 / Collagen IV Alpha2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).