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COL4A1 / Collagen IV Alpha1

collagen, type IV, alpha 1

COL4A1 / Collagen IV Alpha1 is a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.

Gene Name: collagen, type IV, alpha 1
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL4A1, Arresten, COL4A1 NC1 domain, Collagen alpha-1(IV) chain, Collagen, type IV, alpha 1, HANAC, ICH, POREN1
Target Sequences: NM_001845 NP_001836.3 P02462

Publications (1)

1
Defining the Extracellular Matrix of Rhabdomyosarcoma. Xiaolei Lian, J Steffan Bond, Narendra Bharathy, Sergei P Boudko, Elena Pokidysheva, Jack F Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H Gultekin, Noah E Berlow, Charles Keller. Frontiers in oncology. 2021 March;11:601957. [Full Text Article] [PubMed:33708626] [PMC:PMC7942227] Related Antibodies: LS-C175972.

☰ Filters
Products
ELISA Kits (23)
Cell-Based (1)
Custom (2)
Sandwich (16)
Sandwich CLIA (4)
COL4A1 / Collagen IV Alpha1 (23)
Human (9)
Mouse (6)
Rat (4)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (4)
96-Well Strip Plate (16)
No (23)
Adherent Cell Cultures (1)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (16)
Serum (16)
Tissue Homogenates (6)
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
COL4A1 / Collagen IV Alpha1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
4.69 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
0.14 - 100 ng/ml
Chemiluminescent
Plasma, Serum, Tissue Homogenates
1 Plate/$968
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
10 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$958
COL4A1 / Collagen IV Alpha1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).