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COL14A1 / Collagen XIV

collagen, type XIV, alpha 1

Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.

Gene Name: collagen, type XIV, alpha 1
Family/Subfamily: Collagen
Synonyms: COL14A1, Collagen, type XIV, alpha 1, Undulin, Collagen alpha-1(XIV) chain
Target Sequences: NM_021110 NP_066933.1 Q05707

Publications (1)

1
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H. Nature communications. 2016 7:12503. (IHC, WB, ELISA; Human) [Full Text Article] [PubMed:27527664] [PMC:PMC4990710] Related Antibodies: LS-C119470.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).