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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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COL11A2 / Collagen XI

collagen, type XI, alpha 2

COL11A2 / Collagen XI is one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

Gene Name: collagen, type XI, alpha 2
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL11A2, Collagen XI alpha 2, Collagen alpha-2(XI) chain, DFNA13, FBCG2, PARP, Collagen, type XI, alpha 2, DFNB53, HKE5, STL3
Target Sequences: NM_080680 NP_542411.2 P13942

Filtered By: None
Target
COL11A2 / Collagen XI (12)
Reactivity
Human (12)
Mouse (6)
Rat (2)
Bovine (4)
Dog (5)
Monkey (1)
Pig (1)
Zebrafish (1)
Application
IHC (4)
IHC-P (2)
WB (9)
ELISA (1)
IF (1)
Peptide-ELISA (3)
Host
rabbit (10)
goat (2)
Isotype
IgG (7)
Clonality
polyclonal pc (12)
Format
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (9)
Epitope
aa323-372 (4)
1180-1260 aa, C-terminal (1)
C-Terminus (1)
Pro1232 (1)
aa1211-1260 (1)
aa223-237 (1)
aa256-268 (1)
Publications
No (12)
Showing 1-12 of 12 results

COL11A2 / Collagen XI Antibody LS-C393237
Rabbit Polyclonal to Human COL11A2 / Collagen XI
Mouse, Rat, Human
IF IHC IHC-P WB
Unconjugated
100µl  $305.00

COL11A2 / Collagen XI Antibody (1180-1260 aa, C-terminal) LS-C382796
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Mouse, Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of COL11A2 antibody
Western blot of COL11A2 antibody

COL11A2 / Collagen XI Antibody (Pro1232) LS-C193132
Rabbit Polyclonal to Human COL11A2 / Collagen XI
Mouse, Human
IHC WB
Unconjugated
100µl  $385.00

COL11A2 / Collagen XI Antibody (aa1211-1260) LS-C119468
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Mouse, Human
IHC IHC-P Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Collagen XI alpha2 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Collagen XI alpha2 Antibody. The picture on the right is blocked with the synthesized peptide.

COL11A2 / Collagen XI Antibody (aa323-372) LS-C107795
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Dog, Bovine, Human
WB
Unconjugated
50µg  $365.00
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

COL11A2 / Collagen XI Antibody (aa323-372, HRP) LS-C453567
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Dog, Bovine, Human
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

COL11A2 / Collagen XI Antibody (aa323-372, Biotin) LS-C453565
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Dog, Bovine, Human
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

COL11A2 / Collagen XI Antibody (aa323-372, FITC) LS-C453566
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Dog, Bovine, Human
WB
FITC Conjugated
100µl 1mg/ml  $385.00
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
COL11A2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

COL11A2 / Collagen XI Antibody (C-Terminus) LS-C358458
Rabbit Polyclonal to Human COL11A2 / Collagen XI
Zebrafish, Pig, Dog, Human, Monkey
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Collagen 11 alpha 2 expression in COLO205 (A) whole cell lysates.
Western blot analysis of Collagen 11 alpha 2 expression in COLO205 (A) whole cell lysates.

COL11A2 / Collagen XI Antibody LS-C497184
Rabbit Polyclonal (IgG) to Human COL11A2 / Collagen XI
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using COL11A2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of various cell lines, using COL11A2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.

COL11A2 / Collagen XI Antibody (aa223-237) LS-C54666
Goat Polyclonal to Human COL11A2 / Collagen XI
Human
Peptide-ELISA
Unconjugated
100µg  $335.00

COL11A2 / Collagen XI Antibody (aa256-268) LS-C186466
Goat Polyclonal to Human COL11A2 / Collagen XI
Mouse, Human
Peptide-ELISA
Unconjugated
100µg 0.5mg/ml  $335.00
Showing 1-12 of 12 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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