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COIL / Coilin
coilin
COIL / Coilin is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
| Gene Name: | coilin |
| Synonyms: | COIL, Coilin p80, CLN80, Coilin, p80-coilin, p80 |
| Target Sequences: | NM_004645 NP_004636.1 P38432 |
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