CNTNAP2 / CASPR2

contactin associated protein-like 2

CNTNAP2 / CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.

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Products

Proteins (8)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (4)

Target

CNTNAP2 / CASPR2 (8)

Application

SDS-PAGE (1)

Publications

No (8)

Tag

His, N-Terminal (3)

His,C-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (2)

Source

293T Cells (1)

HEK 293 Cells (7)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (1)

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Mouse CNTNAP2 / CASPR2 Protein (Recombinant His,C-terminus) (Met1-Ser1262) - LS-G49539

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant mouse CASPR2 comprises 1246 amino acids and has a calculated molecular mass of 139 kDa. The recombinant protein migrates as an approximately 140-150 kDa band in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$480

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Human CNTNAP2 / CASPR2 Protein (Recombinant His, N-Terminal) (Ala28-Ala1262) - LS-G136138

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~150 kDa

Price:

10 µg/$289; 50 µg/$360; 100 µg/$432

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Human CNTNAP2 / CASPR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88925

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148 kDa

Price:

20 µg/$150

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CNTNAP2 / CASPR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101162

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148 kDa

Price:

100 µg/$494

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Mouse CNTNAP2 / CASPR2 Protein (Recombinant His,C-terminus) (Met1-Ser1262) - LS-G138321

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

139 kDa

Price:

100 µg/$843

Select

Human CNTNAP2 / CASPR2 Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Ala28-Ala1262) - LS-G136136

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~138 kDa

Price:

200 µl/$283

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Human CNTNAP2 / CASPR2 Protein (Over-Expression Lysate His, N-Terminal) (Ala28-Ala1262) - LS-G136137

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~138 kDa

Price:

100 µg/$297

Select

Human CNTNAP2 / CASPR2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71131

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

148 kDa

Price:

20 µg/$1,107

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