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CNTNAP1 / CASPR / p190

contactin associated protein 1

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Gene Name: contactin associated protein 1
Family/Subfamily: Neurexin , Not assigned-Other
Synonyms: CNTNAP1, CASPR, Caspr1, Contactin associated protein 1, CNTNAP, Contactin-associated protein 1, Neurexin IV, Neurexin-4, Neurexin 4, NRXN4, p190
Target Sequences: NM_003632 NP_003623.1 P78357

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Products
Proteins (5)
Over-Expression Lysate (1)
Recombinant (4)
CNTNAP1 / CASPR / p190 (5)
No (5)
GST, N-terminus (1)
His-SUMO (1)
His-T7 (2)
Myc-DDK (Flag) (1)
Human (4)
Mouse (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
CNTNAP1 / CASPR / p190 Protein - Recombinant Contactin Associated Protein 1 By SDS-PAGE
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E. coli
His-T7
33.5 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CNTNAP1 / CASPR / p190 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
156.27 kDa
100 µg/$710
CNTNAP1 / CASPR / p190 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CNTNAP1 / CASPR / p190 Protein - Recombinant  Contactin Associated Protein 1 By SDS-PAGE
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E. coli
His-T7
32.3 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
CNTNAP1 / CASPR / p190 Protein
Select
E. coli
His-SUMO
53.82 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).