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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CNTF

ciliary neurotrophic factor

CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Gene Name: ciliary neurotrophic factor
Synonyms: CNTF, Ciliary neurotrophic factor, HCNTF
Target Sequences: NM_000614 NP_000605.1 P26441

Publications (1)

1
Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation. Kole C, Klipfel L, Yang Y, Ferracane V, Blond F, Reichman S, Millet-Puel G, Clérin E, Aït-Ali N, Pagan D, Camara H, Delyfer MN, Nandrot EF, Sahel JA, Goureau O, Léveillard T. Molecular therapy : the journal of the American Society of Gene Therapy. 2018 January;26:219-237. [Full Text Article] [PubMed:28988713] [PMC:PMC5762984]

Filtered by: None
Type
Over-Expression Lysate (2)
Recombinant (37)
Target
CNTF (39)
Tag
GST (1)
His (6)
His + S (1)
His + T7 (1)
His, N-Terminal (2)
Myc + DDK (3)
Species
Human (23)
Mouse (4)
Pig (1)
Rabbit (1)
Rat (7)
Source
293T Cells (1)
E. coli (32)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purification
Purified (32)
Low Endotoxin Level
Low endotoxin level (18)
Biologically Active
Biologically active (25)
Animal-free
Animal-free (4)
Publications
No (39)
Showing 1-25 of 39 results

Human CNTF Protein (Recombinant) - LS-G16784
E. coli
None
Biologically active
22.706 kDa
5µg  $195.00; 20µg  $255.00; 1mg  $2,850.00

Rat CNTF Protein (Recombinant) - LS-G17047
E. coli
None
Biologically active
22.834 kDa
5µg  $195.00; 25µg  $255.00; 1mg  $2,850.00

Pig CNTF Protein (Recombinant His + S) (aa1-200) - LS-G23812
E. coli
His + S
26.4 kDa
10µg  $305.00; 50µg  $530.00; 100µg  $725.00; 200µg  $1,065.00; 1mg  $2,745.00; 500µg  $1,215.00
Recombinant  Ciliary Neurotrophic Factor By SDS-PAGE

Rabbit CNTF Protein (Recombinant His + T7) (aa1-199) - LS-G23813
E. coli
His + T7
26.4kd
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00; 500µg  $1,140.00
Recombinant  Ciliary Neurotrophic Factor By SDS-PAGE

Human CNTF Protein (Recombinant His) (aa4-196) - LS-G22304
E. coli
His
26.2 kD
1mg  $1,290.00; 500µg  $830.00; 200µg  $485.00; 50µg  $275.00; 10µg  $245.00; 100µg  $355.00

Human CNTF Protein (Recombinant) - LS-G4213
E. coli
None
Biologically active
22.834 kDa
20µg  $355.00; 1mg  $4,500.00; 100µg  $845.00

Human CNTF Protein (Recombinant GST) (Full Length) - LS-G27972
Wheat Germ Extract
GST
49.3 kDa
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE of human CNTF stained with Coomassie Blue

Human CNTF Protein (Recombinant Myc + DDK) (Full Length) - LS-G65258
HEK 293 Cells
Myc + DDK
22.8 kDa
20µg  $890.00
Purified recombinant protein CNTF was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human CNTF Protein (Recombinant) - LS-G37747
None
Biologically active
22.7 kD
20µg  $395.00

Rat CNTF Protein (Recombinant) - LS-G37870
None
Biologically active
22.7 kDa
25µg  $405.00

Mouse CNTF Protein (Recombinant) - LS-G16695
E. coli
None
Biologically active
22.6 kDa
5µg  $195.00; 25µg  $255.00; 1mg  $2,850.00

Human CNTF Protein (Recombinant) - LS-G27102
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
22.8 kDa (SDS-PAGE)
50µg  $295.00; 10µg  $215.00; 1mg  $1,395.00

Human CNTF Protein (Recombinant) - LS-G4207
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
22.9 kDa
20µg  $345.00; 1mg  $4,350.00; 100µg  $845.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human CNTF Protein (Recombinant) - LS-G446
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
22.8 kDa
5µg  $215.00; 20µg  $285.00

Human CNTF Protein (Recombinant) - LS-G3619
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5µg  $225.00; 20µg  $295.00

Human CNTF Protein (Recombinant) - LS-G1380
E. coli
None
100µg 1mg/ml  $315.00; 0.5mg 1mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Rat CNTF Protein (Recombinant) - LS-G477
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
22.7 kDa
5µg  $215.00; 25µg  $285.00

Rat CNTF Protein (Recombinant) - LS-G3706
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5µg  $225.00; 25µg  $295.00

Human CNTF Protein (Recombinant) (aa1-200) - LS-G5826
E. coli
None
Biologically active
22.9 kDa
5µg  $225.00; 20µg  $315.00; 100µg  $770.00; 250µg  $1,380.00; 1mg  $2,445.00; 500µg  $1,785.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse CNTF Protein (Recombinant) - LS-G136317
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
22.6 kDa
100µg  $680.00; 1mg  $3,705.00; 20µg  $285.00; 500µg  $2,040.00; 5µg  $205.00
Proliferation Image
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Mouse CNTF Protein (Recombinant) - LS-G136345
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
22.6 kDa
100µg  $620.00; 1mg  $3,375.00; 20µg  $275.00; 500µg  $1,845.00; 5µg  $205.00
Proliferation Image
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human CNTF Protein (Recombinant) - LS-G137582
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
The 199 amino acid recombinant protein has a predicted molecular mass of approximately 22.8 kD. The predicted N-terminal amino acid is Ala.
20µg  $295.00

Rat CNTF Protein (Recombinant His) (aa2-200) - LS-G16388
E. coli
His
26.2 kDa
10µg  $275.00; 50µg  $455.00; 100µg  $605.00; 200µg  $875.00; 1mg  $2,265.00; 500µg  $1,005.00

Mouse CNTF Protein (Recombinant His) (aa2-198) - LS-G16387
E. coli
His
24.0 kDa
10µg  $275.00; 50µg  $455.00; 100µg  $590.00; 200µg  $875.00; 1mg  $2,235.00; 500µg  $995.00
Recombinant Ciliary Neurotrophic Factor By SDS-PAGE

Human CNTF Protein (Recombinant His) - LS-G16990
E. coli
His
25.0 kDa
5µg  $195.00; 20µg  $255.00; 1mg  $3,780.00
Showing 1-25 of 39 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).