CNOT6L

CCR4-NOT Transcription Complex, Subunit 6-like

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA. Its mRNA deadenylase activity can be inhibited by TOB1. Mediates cell proliferation and cell survival and prevents cellular senescence.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

CNOT6L (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human CNOT6L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83778

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.8 kDa

Price:

20 µg/$215

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CNOT6L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106992

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.8 kDa

Price:

100 µg/$710

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Human CNOT6L Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69064

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.8 kDa

Price:

20 µg/$1,107

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