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CNOT6

CCR4-NOT transcription complex, subunit 6

Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. The increase of ligand-dependent ESR1-mediated transcription is much smaller, if any. Mediates cell proliferation and cell survival and prevents cellular senescence.

Gene Name: CCR4-NOT transcription complex, subunit 6
Synonyms: CNOT6, KIAA1194, Cytoplasmic deadenylase
Target Sequences: NM_015455 NP_056270.2 Q9ULM6

☰ Filters
Products
Antibodies (16)
Primary (16)
CNOT6 (16)
Human (16)
Mouse (1)
Rat (1)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
WB (8)
DB (2)
ELISA (8)
Peptide-ELISA (1)
rabbit (7)
mouse (9)
IgG (7)
IgG2b (3)
IgG2b,k (6)
monoclonal mc (9)
polyclonal pc (7)
2193C2a (2)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (8)
aa35-84 (4)
aa112-211 (1)
No (16)
CNOT6 Antibody - Western blot analysis of immunized recombinant protein, using anti-CNOT6 monoclonal antibody.
Select
CNOT6 Mouse anti-Human Monoclonal (2193C2a) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
Select
CNOT6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$386
CNOT6 Antibody - Western blot analysis of extracts of Jurkat cells using CNOT6 antibody. The lane on the left was treated with blocking peptide.
Select
CNOT6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CNOT6 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µg/$786
Select
CNOT6 Mouse anti-Human Monoclonal (aa112-211) Antibody
Human
ELISA
Unconjugated
100 µg/$705
Select
CNOT6 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
100 µl/$904
Select
CNOT6 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$904
Select
CNOT6 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
100 µl/$904
Select
CNOT6 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA
PE Conjugated
100 µl/$904
Select
CNOT6 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$904
Select
CNOT6 Mouse anti-Human Monoclonal (2193C2a) Antibody
Human
DB
Unconjugated
100 µg/$965
CNOT6 Antibody - CNOT6 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CNOT6 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
CNOT6 Antibody - CNOT6 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CNOT6 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Chicken, Bovine, Rabbit, Dog, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CNOT6 Antibody - CNOT6 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CNOT6 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Chicken, Bovine, Rabbit, Dog, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
CNOT6 Antibody - CNOT6 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CNOT6 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Chicken, Bovine, Rabbit, Dog, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
CNOT6 Antibody - Anti-CNOT6 rabbit polyclonal antibody at 1:500 dilution. Lane A: Jurkat Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 63 kDa. Observed band size: 72 kDa.
Select
CNOT6 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
WB
Unconjugated, Preservative Free
100 µl/$412
Viewing 1-16 of 16 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).