CNOT3

CCR4-NOT transcription complex, subunit 3

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CNOT3 (4)

Publications

No (4)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human CNOT3 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G59424

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CNOT3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87170

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.7 kDa

Price:

20 µg/$150

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Human CNOT3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70474

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.7 kDa

Price:

20 µg/$1,107

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CNOT3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113885

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.7 kDa

Price:

100 µg/$494

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