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Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
Gene Name: | CCR4-NOT transcription complex, subunit 11 |
Synonyms: | CNOT11, C2orf29, C40, UPF0760 protein C2orf29 |
Target Sequences: | NM_017546 NP_060016.3 Q9UKZ1 |
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