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CNN1 / Calponin

calponin 1, basic, smooth muscle

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Gene Name:	calponin 1, basic, smooth muscle
Synonyms:	CNN1, Basic calponin, Calponin, Calponin-1, Calponins, basic, Calponin H1, smooth muscle, SMCC, Sm-Calp
Target Sequences:	NM_001299 NP_001290.2 P51911

Publications (2)

Proteomic analysis of porcine mesenchymal stem cells derived from bone marrow and umbilical cord: implication of the proteins involved in the higher migration capability of bone marrow mesenchymal stem cells. Huang L, Niu C, Willard B, Zhao W, Liu L, He W, Wu T, Yang S, Feng S, Mu Y, Zheng L, Li K. Stem cell research & therapy. 2015 6:77. (ICC; Human) [Full Text Article] [PubMed:25889491]

GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure. Xue Bai, Kevin Mangum, Masao Kakoki, Oliver Smithies, Christopher P Mack, Joan M Taylor. Small GTPases. 2020 May;11:194-203. [Full Text Article] [PubMed:29099324] [PMC:PMC7549679]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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