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CMPK / CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.

Gene Name:	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
Family/Subfamily:	Non-protein Kinase , Adenylate kinase
Synonyms:	CMPK1, CMPK, Deoxycytidylate kinase, Cytidine monophosphate kinase, RP11-511I2.1, UMP-CMPK, UMP/CMP kinase, Uridine monophosphate kinase, UCK, UMK, UMP-CMP kinase, UMP/CMPK, CMK, Cytidylate kinase, UMPK
Target Sequences:	NM_016308 NP_057392.1 P30085

Publications (1)

Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients. Liu NQ, De Marchi T, Timmermans A, Trapman-Jansen AM, Foekens R, Look MP, Smid M, van Deurzen CH, Span PN, Sweep FC, Brask JB, Timmermans-Wielenga V, Foekens JA, Martens JW, Umar A. Scientific reports. 2016 August;6:32027. [Full Text Article] [PubMed:27558661] [PMC:PMC4997324] Related Antibodies: LS-C174314.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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