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CLECSF6 / DCIR is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Gene Name: | C-type lectin domain family 4, member A |
Synonyms: | CLEC4A, C-type lectin DDB27, CLECSF6, DDB27, Dendritic cell immunoreceptor, Lectin-like immunoreceptor, DCIR, HDCGC13P, LLIR |
Target Sequences: | NM_016184 NP_057268.1 Q9UMR7 |
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