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CLEC7A / Dectin 1

C-type lectin domain family 7, member A

Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation.

Gene Name: C-type lectin domain family 7, member A
Synonyms: CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1, CD369
Target Sequences: NM_022570 NP_072092.2 Q9BXN2

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (7)
Recombinant (5)
CLEC7A / Dectin 1 (12)
No (12)
Fc, N-terminus (1)
GST (1)
His (1)
Human IgG1 Fc (1)
Myc-DDK (Flag) (7)
Human (7)
Mouse (2)
293T Cells (4)
HEK 293 Cells (4)
Human Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (4)
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.01 EU/µg protein (determined by LAL method).
~56kDa (SDS-PAGE)
50 µg/$414
CLEC7A / Dectin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
27.4 kDa
20 µg/$150
CLEC7A / Dectin 1 Protein - 12.5% SDS-PAGE of human CLEC7A stained with Coomassie Blue
Select
Wheat Germ Extract
GST
34.21 kDa
10 µg/$479; 25 µg/$670
CLEC7A / Dectin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
19 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
8.2 kDa
20 µg/$150
CLEC7A / Dectin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
8.2 kDa
20 µg/$150
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
15.5 kDa
100 µg/$926
CLEC7A / Dectin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
27.4 kDa
100 µg/$494
CLEC7A / Dectin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
8.2 kDa
100 µg/$494
CLEC7A / Dectin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
19 kDa
100 µg/$494
Select
Mammalian Cells
Fc, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
46.9 kDa
10 µg/$281; 50 µg/$389
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
22.5 kDa
100 µg/$721
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).