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CLEC4E / MINCLE

C-type lectin domain family 4, member E

C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Gene Name: C-type lectin domain family 4, member E
Synonyms: CLEC4E, CLECSF9, MINCLE
Target Sequences: NM_014358 NP_055173.1 Q9ULY5

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
CLEC4E / MINCLE (8)
No (8)
6His, C-terminus (2)
6His, N-terminus (1)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (2)
Select
HEK 293 Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
21.7kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
CLEC4E / MINCLE Protein - 12.5% SDS-PAGE of human CLEC4E stained with Coomassie Blue
Select
Wheat Germ Extract
GST
49.83 kDa
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$150
CLEC4E / MINCLE Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
100 µg/$494
CLEC4E / MINCLE Protein - Purified recombinant protein CLEC4E was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.9 kDa
20 µg/$1,107
CLEC4E / MINCLE Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
CLEC4E / MINCLE Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
21.7 kDa
10 µg/$288; 50 µg/$436
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).