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CLEC1B / CLEC-2

C-type lectin domain family 1, member B

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]

Gene Name: C-type lectin domain family 1, member B
Synonyms: CLEC1B, C-type lectin-like receptor 2, C-type lectin-like receptor-2, CLEC-2, CLEC2, QDED721, PRO1384
Target Sequences: NM_016509 NP_057593.3 Q9P126

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Products
Proteins (8)
Over-Expression Lysate (3)
Recombinant (5)
CLEC1B / CLEC-2 (8)
No (8)
GST (1)
GST, N-terminus (1)
His (1)
His,N-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
293T Cells (2)
CHO Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (2)
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HEK 293 Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.7 kDa
100 µg/$926; 1 mg/$4,903
CLEC1B / CLEC-2 Protein - 12.5% SDS-PAGE of human CLEC1B stained with Coomassie Blue
Select
Wheat Germ Extract
GST
49.5 kDa
2 µg/$439
Select
293T Cells
Myc-DDK (Flag)
22.9 kDa
20 µg/$150
CLEC1B / CLEC-2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.9 kDa
20 µg/$150
CLEC1B / CLEC-2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.9 kDa
100 µg/$494
CLEC1B / CLEC-2 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
CLEC1B / CLEC-2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CLEC1B / CLEC-2 Protein - Recombinant mouse CLEC2-Fc chimera, when coated on a plate, is able to bind biotinylated recombinant mouse GP38-Fc protein in a dose dependent manner. The apparent Kd value of this binding is <5.0 nM.
Select
CHO Cells
None
Less than 1 EU/µg (determined by LAL method).
The 409 amino acid recombinant protein has a predicted molecular mass of approximately 46.7 kD. The protein migrates at about 60 kD by SDS-PAGE in DTT-reducing conditions and about 120 kD in non-reducing conditions. The predicted N-terminal amino acid is
25 µg/$352; 100 µg/$675
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).