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CLEC1B / CLEC-2
C-type lectin domain family 1, member B
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
| Gene Name: | C-type lectin domain family 1, member B |
| Synonyms: | CLEC1B, C-type lectin-like receptor 2, C-type lectin-like receptor-2, CLEC-2, CLEC2, QDED721, PRO1384 |
| Target Sequences: | NM_016509 NP_057593.3 Q9P126 |
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