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CLEC16A / KIAA0350
C-type lectin domain family 16, member A
Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.
| Gene Name: | C-type lectin domain family 16, member A |
| Synonyms: | CLEC16A, KIAA0350, Gop-1, Protein CLEC16A |
| Target Sequences: | AB002348 Q2KHT3 Q2KHT3 |
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