CLDN11 / Claudin 11

claudin 11

CLDN11 / Claudin 11 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CLDN11 / Claudin 11 (5)

Publications

No (5)

Tag

Fc (1)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (1)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human CLDN11 / Claudin 11 Protein (Recombinant GST, N-terminus) (aa28-82) - LS-G59481

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CLDN11 / Claudin 11 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88400

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.8 kDa

Price:

20 µg/$150

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Human CLDN11 / Claudin 11 Protein (Recombinant Fc) (Val23-Arg82) - LS-G97314

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.2 kDa

Price:

100 µg/$843

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Human CLDN11 / Claudin 11 Protein (Recombinant GST) (Full Length) - LS-G29589

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.4 kDa

Price:

2 µg/$439

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CLDN11 / Claudin 11 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115857

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.8 kDa

Price:

100 µg/$494

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