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CLDN11 / Claudin 11

claudin 11

CLDN11 / Claudin 11 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: claudin 11
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN11, Claudin-11, OSP, OTM, Claudin 11
Target Sequences: NM_005602 NP_005593.2 O75508

Publications (1)

1
Restoration of desmosomal junction protein expression and inhibition of H3K9-specific histone demethylase activity by cytostatic proline-rich polypeptide-1 leads to suppression of tumorigenic potential in human chondrosarcoma cells. Galoian K, Qureshi A, Wideroff G, Temple HT. Molecular and clinical oncology. 2015 3:171-178. (WB; Human) [Full Text Article] [PubMed:25469290] [PMC:PMC4251108] Related Antibodies: LS-C6168.

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Products
Antibodies (26)
Primary (26)
CLDN11 / Claudin 11 (26)
Human (26)
Mouse (18)
Rat (15)
Bat (3)
Bovine (4)
Chicken (1)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
Rabbit (4)
IHC (9)
IHC-P (7)
WB (24)
Flo (1)
ELISA (11)
IF (11)
IP (6)
Peptide-ELISA (1)
rabbit (26)
Product Group
IHCPlus (4)
IgG (15)
polyclonal pc (26)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
C-Terminus (7)
130-210 aa, C-terminal (1)
Ser198 (1)
aa158-207 (1)
No (25)
Yes (1)
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$740
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
ELISA, IF, IP, WB
HRP Conjugated
100 µl/$982
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$982
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$982
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$982
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$982
CLDN11 / Claudin 11 Antibody - Immunohistochemistry of paraffin-embedded human kidney cancer using CLDN11 antibody at dilution of 1:200 (x400 lens).
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CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CLDN11 / Claudin 11 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (aa158-207) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
CLDN11 / Claudin 11 Antibody - Anti-CLDN11 / Claudin 11 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CLDN11 / Claudin 11 Antibody - Anti-CLDN11 / Claudin 11 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CLDN11 / Claudin 11 Antibody - Anti-CLDN11 / Claudin 11 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CLDN11 / Claudin 11 Antibody - Anti-CLDN11 / Claudin 11 antibody IHC of human brain, cortex, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CLDN11 / Claudin 11 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
CLDN11 / Claudin 11 Antibody - Western blot of Claudin 11 (S198) pAb in extracts from mouse brain.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (Ser198) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CLDN11 / Claudin 11 Antibody - Anti-CLDN11 / Claudin 11 antibody IHC of human testis, sertoli cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
250 µl/$505
CLDN11 / Claudin 11 Antibody - Western blot of Claudin 11 expression in Mouse brain extract
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal (130-210 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CLDN11 / Claudin 11 Antibody - Western blot analysis of extracts from mouse brain, using Claudin 11 antibody.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CLDN11 / Claudin 11 Antibody - Western blot analysis of mouse-kidney lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CLDN11 / Claudin 11 Antibody - Immunofluorescence analysis of U2OS cells using CLDN11 Polyclonal Antibody.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
CLDN11 / Claudin 11 Antibody - Western blot analysis of extracts of various cell lines, using CLDN11 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
CLDN11 / Claudin 11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).