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CLCNKB

chloride channel, voltage-sensitive Kb

CLCNKB is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: chloride channel, voltage-sensitive Kb
Family/Subfamily: Ion Channel , Chloride channel - CLCK
Synonyms: CLCNKB, Bartter syndrome Type 3, Chloride channel, kidney, B, Chloride channel Kb, ClC-Kb, ClC-K2, CLCKB, HClC-Kb
Target Sequences: NM_000085 NP_000076.2 P51801

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Proteins (2)
Recombinant (2)
CLCNKB (2)
No (2)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
CLCNKB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CLCNKB Protein - 12.5% SDS-PAGE of human CLCNKB stained with Coomassie Blue
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Wheat Germ Extract
GST
77 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).