Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
Gene Name: | chloride channel, voltage-sensitive 1 |
Family/Subfamily: | Ion Channel , Chloride channel - CLC |
Synonyms: | CLCN1, Chloride channel protein 1, ClC-1, SMCC1, Chloride channel 1, CLC1 |
Target Sequences: | NM_000083 NP_000074.2 P35523 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.