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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CLC-7 / CLCN7

chloride channel, voltage-sensitive 7

CLC-7 / CLCN7 belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Gene Name: chloride channel, voltage-sensitive 7
Family/Subfamily: Ion Channel , Chloride channel - CLC
Synonyms: CLCN7, Chloride channel 7, CLC7, OPTA2, Chloride channel protein 7, CLC-7, OPTB4, PPP1R63
Target Sequences: NM_001287 NP_001278.1 P51798

Filtered By: None
Type
Over-Expression Lysate (3)
Recombinant (1)
Target
clc-7-clcn7 (4)
Tag
GST,N-terminus (1)
Myc + DDK (3)
Species
Human (2)
Source
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Showing 1-4 of 4 results

Human CLC-7 / CLCN7 Protein (Recombinant GST,N-terminus) (aa706-805) - LS-G58152
Wheat Germ Extract
100 AA
GST,N-terminus
No
No known endotoxin level
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.
12.5% SDS-PAGE Stained with Coomassie Blue.

CLC-7 / CLCN7 Protein (Over-Expression Lysate Myc + DDK) - LS-G118678
HEK 293 Cells
857 AA
Myc + DDK
No
No known endotoxin level
88.5 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human CLC-7 / CLCN7 Protein (Over-Expression Lysate Myc + DDK) - LS-G75166
293T Cells
857 AA
Myc + DDK
No
No known endotoxin level
88.5 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

CLC-7 / CLCN7 Protein (Over-Expression Lysate Myc + DDK) - LS-G124352
HEK 293 Cells
833 AA
Myc + DDK
No
No known endotoxin level
86 kDa
100µg  $475.00
Showing 1-4 of 4 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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