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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CLC-7 / CLCN7

chloride channel, voltage-sensitive 7

CLC-7 / CLCN7 belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Gene Name: chloride channel, voltage-sensitive 7
Family/Subfamily: Ion Channel , Chloride channel - CLC
Synonyms: CLCN7, Chloride channel 7, CLC7, OPTA2, Chloride channel protein 7, CLC-7, OPTB4, PPP1R63
Target Sequences: NM_001287 NP_001278.1 P51798

Filtered By: None
Target
CLC-7 / CLCN7 (22)
Reactivity
Human (20)
Mouse (9)
Rat (9)
Application
IHC (14)
IHC-P (4)
WB (20)
ELISA (14)
ICC (8)
IF (12)
Peptide-ELISA (2)
Host
rabbit (21)
mouse (1)
Isotype
IgG (17)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (21)
Clone
4A3 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (16)
Epitope
aa692-720 (8)
N-Terminus (3)
C-Terminus (2)
10-90 aa, N-terminal (1)
aa10-59 (1)
aa23-72 (1)
aa33-78 (1)
Publications
No (22)
Showing 1-22 of 22 results

CLC-7 / CLCN7 Antibody (aa10-59) IHC-plus™ LS-B13431
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
100µl 1mg/ml  $505.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

CLC-7 / CLCN7 Antibody (N-Terminus) LS-C352017
Rabbit Polyclonal to Human CLC-7 / CLCN7
Mouse, Rat, Human
ICC IF WB
Unconjugated
100µl 1mg/ml  $245.00
Immunofluorescent analysis of CLCN7 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Western blot analysis of CLCN7 expression in HeLa (A); mouse liver (B); rat liver (C) whole cell lysates.
Immunofluorescent analysis of CLCN7 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Western blot analysis of CLCN7 expression in HeLa (A); mouse liver (B); rat liver (C) whole cell lysates.

CLC-7 / CLCN7 Antibody (C-Terminus) LS-C6136
Rabbit Polyclonal (IgG) to Rat CLC-7 / CLCN7
Mouse, Rat
ELISA WB
Unconjugated
100µl  $725.00

CLC-7 / CLCN7 Antibody (aa23-72) IHC-plus™ LS-B14661
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

CLC-7 / CLCN7 Antibody (aa692-720) LS-C320417
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA IF IHC WB
Unconjugated
200µl  $530.00

CLC-7 / CLCN7 Antibody (aa692-720, Biotin) LS-C254941
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
Biotin Conjugated
200µl  $680.00

CLC-7 / CLCN7 Antibody (aa692-720, FITC) LS-C254942
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
FITC Conjugated
200µl  $680.00

CLC-7 / CLCN7 Antibody (aa692-720, AP) LS-C254939
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
AP Conjugated
200µl  $680.00

CLC-7 / CLCN7 Antibody (aa692-720, APC) LS-C254940
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
APC Conjugated
200µl  $680.00

CLC-7 / CLCN7 Antibody (aa692-720, Azide-free, HRP) LS-C254943
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

CLC-7 / CLCN7 Antibody (aa692-720, PE) LS-C254945
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
PE Conjugated
200µl  $680.00

CLC-7 / CLCN7 Antibody (aa692-720) LS-C168806
Rabbit Polyclonal to Human CLC-7 / CLCN7
Human
IF IHC IHC-P WB
Unconjugated
400µl  $305.00
CLCN7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of CLCN7 Antibody with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
CLCN7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of CLCN7 Antibody with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

CLC-7 / CLCN7 Antibody (N-Terminus) LS-C6139
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA IF IHC WB
Unconjugated
100µg  $755.00

CLC-7 / CLCN7 Antibody LS-C412579
Rabbit Polyclonal to Human CLC-7 / CLCN7
Mouse, Rat, Human
IF IHC WB
Unconjugated
100µl  $385.00

CLC-7 / CLCN7 Antibody LS-C675544
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA IHC IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100

CLC-7 / CLCN7 Antibody (clone 4A3) LS-C196932
Mouse Monoclonal [clone 4A3] (IgG2a,k) to Human CLC-7 / CLCN7
Human
ELISA WB
Unconjugated
50µg  $355.00

CLC-7 / CLCN7 Antibody (aa33-78) LS-C313714
Rabbit Polyclonal to Human CLC-7 / CLCN7
Mouse, Rat, Human
ICC WB
Unconjugated
100µl  $345.00

CLC-7 / CLCN7 Antibody LS-C346131
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded mouse brain tissue.
Western blot analysis of extracts of various cell lines.
Immunohistochemistry of paraffin-embedded mouse brain tissue.
Western blot analysis of extracts of various cell lines.

CLC-7 / CLCN7 Antibody (N-Terminus) LS-C6138
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA WB
Unconjugated
100µl  $725.00

CLC-7 / CLCN7 Antibody (10-90 aa, N-terminal) LS-C382747
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of CLC-7 antibody
Western blot of CLC-7 antibody

CLC-7 / CLCN7 Antibody LS-C747525
Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
IF
Unconjugated
50µl  $235.00

CLC-7 / CLCN7 Antibody (C-Terminus) LS-C6137
Rabbit Polyclonal (IgG) to Rat CLC-7 / CLCN7
Mouse, Rat
ELISA WB
Unconjugated
100µg  $755.00
Showing 1-22 of 22 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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