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CLC-7 / CLCN7

chloride channel, voltage-sensitive 7

CLC-7 / CLCN7 belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Gene Name: chloride channel, voltage-sensitive 7
Family/Subfamily: Ion Channel , Chloride channel - CLC
Synonyms: CLCN7, Chloride channel 7, CLC7, OPTA2, Chloride channel protein 7, CLC-7, OPTB4, PPP1R63
Target Sequences: NM_001287 NP_001278.1 P51798

Filtered By: None
Target
clc-7-clcn7 (21)
Reactivity
Human (19)
Mouse (9)
Rat (9)
Application
IHC (14)
IHC-P (3)
WB (20)
ELISA (14)
ICC (8)
IF (11)
Peptide-ELISA (2)
Host
rabbit (20)
mouse (1)
Isotype
IgG (16)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (20)
Clone
4A3 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (15)
Epitope
aa692-720 (8)
N-Terminus (3)
C-Terminus (2)
aa10-59 (1)
aa10-90 (1)
aa23-72 (1)
aa33-78 (1)
Publications
No (21)
Showing 1-21 out of 21 results
Anti-CLC-7 / CLCN7 Antibody (aa10-59) IHC-plus™ LS-B13431
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (N-Terminus) LS-C352017
Immunofluorescent analysis of CLCN7 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Western blot analysis of CLCN7 expression in HeLa (A); mouse liver (B); rat liver (C) whole cell lysates.

Rabbit Polyclonal to Human CLC-7 / CLCN7
Mouse, Rat, Human
ICC IF WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (C-Terminus) LS-C6136

Rabbit Polyclonal (IgG) to Rat CLC-7 / CLCN7
Mouse, Rat
ELISA WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (aa23-72) IHC-plus™ LS-B14661
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720) LS-C320417

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA IF IHC WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720, Biotin) LS-C254941

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
Biotin Conjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720, FITC) LS-C254942

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
FITC Conjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720, APC) LS-C254940

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
APC Conjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720, Azide-free, HRP) LS-C254943

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
HRP Conjugated, Azide-free
Anti-CLC-7 / CLCN7 Antibody (aa692-720, AP) LS-C254939

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
AP Conjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720, PE) LS-C254945

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA ICC IF IHC WB
PE Conjugated
Anti-CLC-7 / CLCN7 Antibody (N-Terminus) LS-C6139

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA IF IHC WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (aa692-720) LS-C168806
CLCN7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of CLCN7 Antibody with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Rabbit Polyclonal to Human CLC-7 / CLCN7
Human
IF IHC IHC-P WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody LS-C412579

Rabbit Polyclonal to Human CLC-7 / CLCN7
Mouse, Rat, Human
IF IHC WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody LS-C675544
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA IHC
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (clone 4A3) LS-C196932

Mouse Monoclonal [clone 4A3] (IgG2a,k) to Human CLC-7 / CLCN7
Human
ELISA WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (aa33-78) LS-C313714

Rabbit Polyclonal to Human CLC-7 / CLCN7
Mouse, Rat, Human
ICC WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody LS-C346131
Immunohistochemistry of paraffin-embedded mouse brain tissue.
Western blot analysis of extracts of various cell lines.

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
IHC WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (N-Terminus) LS-C6138

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Human
ELISA WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (aa10-90) LS-C382747
Western blot of CLC-7 antibody

Rabbit Polyclonal (IgG) to Human CLC-7 / CLCN7
Mouse, Rat, Human
ELISA WB
Unconjugated
Anti-CLC-7 / CLCN7 Antibody (C-Terminus) LS-C6137

Rabbit Polyclonal (IgG) to Rat CLC-7 / CLCN7
Mouse, Rat
ELISA WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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