CKMT1B

creatine kinase, mitochondrial 1B

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

CKMT1B (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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CKMT1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110842

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43 kDa

Price:

100 µg/$710

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Human CKMT1B Protein (Recombinant His) (aa40-417) - LS-G22483

Source:

E. coli

Tag:

His

Molecular Weight:

47.2 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CKMT1B Protein (Recombinant GST) (Full Length) - LS-G27931

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CKMT1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75324

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43 kDa

Price:

20 µg/$215

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Human CKMT1B Protein (Recombinant GST, N-terminus) (aa327-417) - LS-G58146

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CKMT1B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65312

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43 kDa

Price:

20 µg/$1,107

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