CILP

cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.

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Products

ELISA Kits (6)

Type

Sandwich (6)

Target

CILP (6)

Reactivity

Human (3)

Mouse (1)

Dog (1)

Pig (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (3)

Publications

No (6)

Sample Type

Cell Culture Supernatants (4)

Cell Lysates (1)

Citrate Plasma (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (5)

Serum (6)

Tissue Homogenates (2)

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Mouse CILP (Sandwich ELISA) ELISA Kit - LS-F16332

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Human CILP (Sandwich ELISA) ELISA Kit - LS-F16334

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Pig CILP (Sandwich ELISA) ELISA Kit - LS-F16333

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human CILP (Sandwich ELISA) ELISA Kit - LS-F49891

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.053 - 13 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$700

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Human CILP (Sandwich ELISA) ELISA Kit - LS-F57147

Type:

Sandwich

Reactivity:

Human

Range:

93.8 - 6000 pg/ml

Sample Types:

Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Dog CILP (Sandwich ELISA) ELISA Kit - LS-F74389

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Dog

Range:

15.6 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$646

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