CIDEB

cell death-inducing DFFA-like effector b

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CIDEB (5)

Publications

No (5)

Tag

GST (2)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human CIDEB Protein (Recombinant GST, N-terminus) (aa3-110) - LS-G62244

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CIDEB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113945

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.5 kDa

Price:

100 µg/$494

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Human CIDEB Protein (Recombinant GST) (Full Length) - LS-G33271

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CIDEB Protein (Recombinant GST) (Full Length) - LS-G33273

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

49.83 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CIDEB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85340

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.5 kDa

Price:

20 µg/$150

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