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CIAO1

cytosolic iron-sulfur assembly component 1

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

Gene Name: cytosolic iron-sulfur assembly component 1
Synonyms: CIAO1, CIA1, WDR39, WD repeat domain 39, WD40 protein Ciao1
Target Sequences: NM_004804 NP_004795.1 O76071

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).