CHTOP / FOP

chromatin target of PRMT1

Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.Required for effective mRNA nuclear export and is a component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Stimulates DDX39B ATPase and helicase activities. In cooperation with ALYREF/THOC4 enhances NXF1 RNA binding activity.

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Products

Antibodies (16)

Type

Primary (16)

Target

CHTOP / FOP (16)

Reactivity

Human (13)

Mouse (9)

Rat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Pig (3)

Xenopus (3)

Zebrafish (3)

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Application

IHC (5)

IHC-P (2)

WB (13)

ELISA (5)

ICC (1)

IF (1)

IP (4)

Peptide-ELISA (1)

Host

rabbit (12)

mouse (2)

rat (2)

Product Group

IHCPlus (1)

Isotype

IgG (8)

IgG2a (4)

Clonality

monoclonal mc (4)

polyclonal pc (12)

Clone

KT59 (1)

KT64 (1)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (10)

Epitope

aa71-120 (4)

C-Terminus (2)

N-Terminus (2)

aa1-50 (1)

aa198-248 (1)

Publications

No (15)

Yes (1)

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IHC-plus™ CHTOP / FOP Antibody (C-Terminus, clone KT64) LS-B11259

(4.0) Rating

Antibody:

CHTOP / FOP Rat anti-Mouse Monoclonal (C-Terminus) (KT64) Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

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CHTOP / FOP Antibody (N-Terminus, clone KT59) LS-C193506

(4.0) Rating

(1) Publication(s)

Antibody:

CHTOP / FOP Rat anti-Mouse Monoclonal (N-Terminus) (KT59) Antibody

Reactivity:

Mouse

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$455

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CHTOP / FOP Antibody (aa71-120) LS-C116607

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CHTOP / FOP Antibody (aa71-120, HRP) LS-C459950

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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CHTOP / FOP Antibody (aa71-120, Biotin) LS-C459791

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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CHTOP / FOP Antibody (aa71-120, FITC) LS-C459792

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CHTOP / FOP Antibody (C-Terminus) LS-C123583

Antibody:

CHTOP / FOP Mouse anti-Mouse Monoclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$564

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CHTOP / FOP Antibody LS-C677544

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CHTOP / FOP Antibody (HRP) LS-C677546

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CHTOP / FOP Antibody (Biotin) LS-C677545

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CHTOP / FOP Antibody (FITC) LS-C677547

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CHTOP / FOP Antibody (N-Terminus) LS-C123582

Antibody:

CHTOP / FOP Mouse anti-Mouse Monoclonal (N-Terminus) Antibody

Reactivity:

Mouse

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$564

Select

CHTOP / FOP Antibody LS-C753559

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

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CHTOP / FOP Antibody LS-C808963

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CHTOP / FOP Antibody (aa1-50) LS-C290088

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

CHTOP / FOP Antibody (aa198-248) LS-C290091

Antibody:

CHTOP / FOP Rabbit anti-Human Polyclonal (aa198-248) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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