CHST2

carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.

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Proteins (1)

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Recombinant (1)

Target

CHST2 (1)

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No (1)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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Human CHST2 Protein (Recombinant GST, N-terminus) (aa431-530) - LS-G61124

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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