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CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO4) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

Gene Name: carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Synonyms: CHST15, GALNAC4S-6ST, GALNAC4S6ST, KIAA0598, HBRAG, RP11-47G11.1, BRAG
Target Sequences: AX281669 BAB72145.1 Q7LFX5

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CHST15 (5)
No (5)
GST (1)
His,N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (1)
CHST15 Protein - Purified recombinant protein CHST15 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
64.7 kDa
20 µg/$1,107
CHST15 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
64.7 kDa
20 µg/$150
CHST15 Protein - 12.5% SDS-PAGE of human GALNAC4S-6ST stained with Coomassie Blue
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Wheat Germ Extract
GST
87.45 kDa
2 µg/$439
CHST15 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
64.7 kDa
100 µg/$494
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HEK 293 Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
56 kDa
50 µg/$721
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).