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Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO4) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
Gene Name: | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
Synonyms: | CHST15, GALNAC4S-6ST, GALNAC4S6ST, KIAA0598, HBRAG, RP11-47G11.1, BRAG |
Target Sequences: | AX281669 BAB72145.1 Q7LFX5 |
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