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CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

Gene Name:	carbohydrate (chondroitin 4) sulfotransferase 11
Synonyms:	CHST11, C4ST, C4ST-1, HSA269537, IgH/CHST11 fusion, C4S-1, C4ST1
Target Sequences:	NM_018413 NP_060883.1 Q9NPF2

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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