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CHRNE

cholinergic receptor, nicotinic, epsilon (muscle)

CHRNE encodes the epsilon subunit of the nicotinic acetylcholine receptor (nAChR). The nAChR is an ion-conducting channel of the plasma membrane that transmits signal from motor neuron to skeletal muscle in response to binding acetylcholine. It is composed of four subunits in a stoichiometry of alpha 2, beta 1, delta 1, and gamma or epsilon 1. The epsilon subunit is a component of mature nAChRs, as it replaces the embryonic gamma subunit at neuromuscular junctions in newborns. CHRNE null mice display muscle weakness, defects in motor behavior, and premature death. Mutations in the CHRNE gene are responsible for slow-channel congenital myasthenic syndrome (SCCMS).

Gene Name: cholinergic receptor, nicotinic, epsilon (muscle)
Family/Subfamily: Ion Channel , Nicotinic acetylcholine receptor
Synonyms: CHRNE, ACHRE, AChR-epsilon, AchR epsilon subunit, CMS1D, CMS1E, FCCMS, NAChR epsilon, SCCMS, CMS2A
Target Sequences: NM_000080 NP_000071.1 Q04844

☰ Filters
Products
Antibodies (19)
Primary (19)
CHRNE (19)
Human (10)
Mouse (11)
Rat (2)
IHC (3)
IHC-P (2)
WB (16)
Flo (2)
ELISA (6)
Peptide-ELISA (2)
rabbit (14)
mouse (3)
goat (2)
Ig (1)
IgG (3)
IgG1 (2)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (16)
4E10F6 (1)
5F11G8 (1)
6A2 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
Internal (1)
aa185-196 (1)
aa185-197 (1)
No (19)
Select
CHRNE Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
200 µl/$468
CHRNE Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Select
CHRNE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
CHRNE Mouse anti-Human Monoclonal (5F11G8) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
CHRNE Antibody - All lanes: Anti-CHRNE Antibody (Center) at 1:2000 dilution Lane 1: Human skeletal muslce lysate Lane 2: Mouse skeletal muscle lysate Lane 3: Rat skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
CHRNE Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
CHRNE Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Select
CHRNE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
CHRNE Mouse anti-Human Monoclonal (4E10F6) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
CHRNE Antibody - Detection limit for recombinant GST tagged CHRNE is 0.1 ng/ml as a capture antibody.
Select
CHRNE Mouse anti-Human Monoclonal (6A2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CHRNE Antibody - Western Blot; Sample: Recombinant CHRNe, Mouse.
Select
CHRNE Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CHRNE Antibody
Select
CHRNE Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
CHRNE Antibody - Western blot analysis of extracts of various cell lines, using CHRNE antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
Select
CHRNE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
CHRNE Goat anti-Mouse Polyclonal (aa185-196) Antibody
Mouse
Peptide-ELISA
Unconjugated
100 µg/$401
Select
CHRNE Goat anti-Human Polyclonal (aa185-197) Antibody
Human
Peptide-ELISA
Unconjugated
100 µg/$401
Viewing 1-19 of 19 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).