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CHRNB3

cholinergic receptor, nicotinic, beta 3 (neuronal)

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.

Gene Name: cholinergic receptor, nicotinic, beta 3 (neuronal)
Family/Subfamily: Ion Channel , Nicotinic acetylcholine receptor
Synonyms: CHRNB3, AChR-beta3, NAChR beta 3
Target Sequences: NM_000749 NP_000740.1 Q05901

☰ Filters
Products
Antibodies (32)
Primary (32)
CHRNB3 (32)
Human (32)
Mouse (7)
Rat (10)
Bat (1)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (6)
Gibbon (3)
Guinea pig (6)
Hamster (2)
Horse (4)
Monkey (3)
Pig (3)
Rabbit (4)
IHC (6)
IHC-P (5)
WB (27)
Flo (1)
ELISA (7)
ICC (2)
IF (2)
Peptide-ELISA (2)
RIA (1)
rabbit (29)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (9)
IgG1 (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (30)
3G6 (1)
7C9F12 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (16)
aa119-230 (8)
N-Terminus (4)
aa176-225 (4)
C-Terminus (3)
aa187-200 (1)
aa403-414 (1)
No (32)
CHRNB3 Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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CHRNB3 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
CHRNB3 Antibody - Anti-CHRNB3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (aa176-225) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CHRNB3 Antibody - Anti-CHRNB3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (aa176-225) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CHRNB3 Antibody - Anti-CHRNB3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (aa176-225) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CHRNB3 Antibody - Anti-CHRNB3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (aa176-225) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CHRNB3 Antibody - Immunofluorescence of monoclonal antibody to CHRNB3 on HeLa cell . [antibody concentration 10 ug/ml]
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CHRNB3 Mouse anti-Human Monoclonal (3G6) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
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CHRNB3 Mouse anti-Human Monoclonal (7C9F12) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
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CHRNB3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$717
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CHRNB3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$587
CHRNB3 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CHRNB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CHRNB3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$331
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CHRNB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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CHRNB3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
RIA, WB
Unconjugated
5 ml/$694
CHRNB3 Antibody - Antibody (1 ug/ml) staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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CHRNB3 Goat anti-Human Polyclonal (aa403-414) Antibody
Rat, Hamster, Horse, Bat, Rabbit, Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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CHRNB3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CHRNB3 Antibody - Western blot analysis of extracts of various cell lines, using CHRNB3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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CHRNB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CHRNB3 Antibody - Western blot of lysates from mouse heart, rat brain tissue lysate (from left to right) with CHRNB3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.
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CHRNB3 Rabbit anti-Human Polyclonal (aa187-200) Antibody
Hamster, Human
WB
Unconjugated
400 µl/$393
CHRNB3 Antibody - Western blot of ACHB3 Antibody with human A549 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CHRNB3 Antibody - Western blot of ACHB3 Antibody with human A549 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Dog, Guinea pig, Rat, Pig, Horse, Human
WB
HRP Conjugated
100 µl/$469
CHRNB3 Antibody - Western blot of ACHB3 Antibody with human A549 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Dog, Guinea pig, Rat, Pig, Horse, Human
WB
Biotin Conjugated
100 µl/$469
CHRNB3 Antibody - Western blot of ACHB3 Antibody with human A549 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHRNB3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Dog, Guinea pig, Rat, Pig, Horse, Human
WB
FITC Conjugated
100 µl/$469
CHRNB3 Antibody - Western blot of CHRNB3 antibody.
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CHRNB3 Rabbit anti-Human Polyclonal (aa119-230) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CHRNB3 Antibody - Western blot of CHRNB3 antibody.
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CHRNB3 Rabbit anti-Human Polyclonal (aa119-230) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
CHRNB3 Antibody - Western blot of CHRNB3 antibody.
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CHRNB3 Rabbit anti-Human Polyclonal (aa119-230) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
CHRNB3 Antibody - Western blot of CHRNB3 antibody.
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CHRNB3 Rabbit anti-Human Polyclonal (aa119-230) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
Viewing 1-25 of 32 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).