CHRNA4 / NACHR

cholinergic receptor, nicotinic, alpha 4 (neuronal)

CHRNA4 / NACHR is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

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Products

Proteins (4)

Type

Recombinant (4)

Target

CHRNA4 / NACHR (4)

Publications

No (4)

Tag

GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag), C-terminus (1)

Species

Human (3)

Mouse (1)

Source

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Mouse CHRNA4 / NACHR Protein (Recombinant His-T7) (aa32-249) - LS-G24550

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human CHRNA4 / NACHR Protein (Recombinant His-T7) (aa49-242) - LS-G24549

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.5 kDa

Price:

10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136

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Human CHRNA4 / NACHR Protein (Recombinant Myc-DDK (Flag), C-terminus) (Full Length) - LS-G142150

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag), C-terminus

Molecular Weight:

69.9 kDa

Price:

20 µg/$1,107

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Human CHRNA4 / NACHR Protein (Recombinant GST, N-terminus) (aa29-128) - LS-G58129

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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