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CHP2

calcineurin-like EF-hand protein 2

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

Gene Name: calcineurin-like EF-hand protein 2
Synonyms: CHP2, HCA520
Target Sequences: NM_022097 NP_071380.1 O43745

☰ Filters
Antibodies (6)
Proteins (2)
Over-Expression Lysate (2)
Primary (6)
CHP2 (8)
Human (6)
Mouse (6)
Rat (6)
Monkey (1)
IHC (2)
IHC-P (2)
WB (6)
ELISA (2)
ICC (1)
IF (1)
IP (1)
Peptide-ELISA (2)
rabbit (6)
Product Group
IHCPlus (2)
IgG (4)
polyclonal pc (6)
Unconjugated (6)
70-150 aa, Internal (1)
Internal (1)
aa101-150 (1)
aa146-191 (1)
No (8)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
CHP2 Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CHP2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
CHP2 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CHP2 Rabbit anti-Human Polyclonal (aa146-191) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CHP2 Antibody - Staining HT29 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
CHP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CHP2 Antibody - Western blot of CHP2 antibody
Select
CHP2 Rabbit anti-Human Polyclonal (70-150 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CHP2 Antibody - Western blot analysis of extracts from Jurkat cells, K562 cells and HT-29 cells, using CHP2 antibody.
Select
CHP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CHP2 Antibody - Western blot analysis of lysates from HT-29, K562, and Jurkat cells, using CHP2 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
CHP2 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CHP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
22.3 kDa
20 µg/$150
CHP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
22.3 kDa
100 µg/$494
Viewing 1-8 of 8 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).