CHMP1B

Charged Multivesicular Body Protein 1B

Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

CHMP1B (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (2)

His (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human CHMP1B Protein (Recombinant His) - LS-G1787

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 10 µg/$292; 50 µg/$523; 250 µg/$1,285; 500 µg/$1,917

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Human CHMP1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91257

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.9 kDa

Price:

20 µg/$150

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CHMP1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111174

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.9 kDa

Price:

100 µg/$494

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Human CHMP1B Protein (Recombinant GST) (Full Length) - LS-G34663

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CHMP1B Protein (Recombinant GST, N-terminus) (aa145-199) - LS-G62923

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CHMP1B Protein (Recombinant GST, N-terminus) (aa1-199) - LS-G56785

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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