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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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CHMP1A

charged multivesicular body protein 1A

Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.

Gene Name: charged multivesicular body protein 1A
Family/Subfamily: Protease , Metallopeptidase Other
Synonyms: CHMP1A, Chromatin-modifying protein 1a, Chromatin modifying protein 1A, HVps46-1, Metallopeptidase prsm1, PCH8, Protease, metallo, 1, 33kD, VPS46A, PCOLN3, VPS46-1, CHMP1, KIAA0047, PRSM1
Target Sequences: NM_002768 NP_002759.2 Q9HD42

☰ Filters
IHC (3)
WB (22)
ELISA (12)
IF (3)
IP (1)
IgG (25)
No (27)
Viewing 1-25 of 27 items
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, IHC, IP, WB
Unconjugated
100µg   $375.00
CHMP1A Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl   0.4mg/ml   $205.00; 60µl   0.4mg/ml   $235.00; 120µl   0.4mg/ml   $295.00; 200µl   0.4mg/ml   $395.00
CHMP1A Antibody - IHC image of CHMP1A Antibody diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, IF
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
FITC Conjugated
50µg   $285.00; 100µg   $385.00
CHMP1A Antibody - Western blot analysis of extracts of A431 cells using CHMP1A antibody. The lane on the left was treated with blocking peptide.
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
CHMP1A Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
ELISA, IHC
Unconjugated
20µl   0.4mg/ml   $205.00; 60µl   0.4mg/ml   $235.00; 120µl   0.4mg/ml   $295.00; 200µl   0.4mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Mouse Polyclonal (IgG) to Human CHMP1A
Human
IF, WB
Unconjugated
50µg   $560.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
Unconjugated
100µg   $605.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
HRP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
Biotin Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
FITC Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
AP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
APC Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
PE Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
CHMP1A Antibody - CHMP1A Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The CHMP1A antibody detected the CHMP1A protein (arrow).
Select
Rabbit Polyclonal to Human CHMP1A
Human
WB
Unconjugated
400µl   $325.00
CHMP1A Antibody
Select
Rabbit Polyclonal to Human CHMP1A
Human
WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
CHMP1A Antibody - Western blot analysis of extracts of various cell lines, using CHMP1A antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Select
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00

Viewing 1-25 of 27 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).