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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CHMP1A

charged multivesicular body protein 1A

Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.

Gene Name: charged multivesicular body protein 1A
Family/Subfamily: Protease , Metallopeptidase Other
Synonyms: CHMP1A, Chromatin-modifying protein 1a, Chromatin modifying protein 1A, HVps46-1, Metallopeptidase prsm1, PCH8, Protease, metallo, 1, 33kD, VPS46A, PCOLN3, VPS46-1, CHMP1, KIAA0047, PRSM1
Target Sequences: NM_002768 NP_002759.2 Q9HD42

Filtered By: None
Target
CHMP1A (25)
Reactivity
Human (25)
Mouse (3)
Application
IHC (3)
WB (20)
ELISA (11)
IF (2)
IP (1)
Host
rabbit (24)
mouse (1)
Isotype
IgG (23)
Clonality
polyclonal pc (25)
Format
AP Conjugated (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (10)
Epitope
aa34-61 (8)
Publications
No (25)
Showing 1-25 of 25 results

CHMP1A Antibody LS-C753091
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA IHC IP WB
Unconjugated
100µg  $355.00

CHMP1A Antibody LS-C404816
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human thyroid cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human thyroid cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.

CHMP1A Antibody LS-C671771
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA IF
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunofluorescence staining of HepG2 cells at a dilution of 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
Immunofluorescence staining of HepG2 cells at a dilution of 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

CHMP1A Antibody (HRP) LS-C671772
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

CHMP1A Antibody (Biotin) LS-C671775
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

CHMP1A Antibody (FITC) LS-C671774
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
FITC Conjugated
50µg  $285.00; 100µg  $385.00

CHMP1A Antibody LS-C401526
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human gastric cancer using CHMP1A Polyclonal Antibody at dilution of 1:60.

CHMP1A Antibody (aa34-61) LS-C320356
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
Unconjugated
200µl  $530.00

CHMP1A Antibody (aa34-61, Biotin) LS-C254752
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

CHMP1A Antibody (aa34-61, FITC) LS-C254753
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
FITC Conjugated
200µl  $680.00

CHMP1A Antibody (aa34-61, AP) LS-C254749
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
AP Conjugated
200µl  $680.00

CHMP1A Antibody (aa34-61, APC) LS-C254751
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
APC Conjugated
200µl  $680.00

CHMP1A Antibody (aa34-61, PE) LS-C254755
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
PE Conjugated
200µl  $680.00

CHMP1A Antibody (aa34-61, Azide-free, HRP) LS-C254754
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

CHMP1A Antibody LS-C306945
Mouse Polyclonal (IgG) to Human CHMP1A
Human
IF WB
Unconjugated
50µg  $560.00

CHMP1A Antibody LS-C309908
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
Unconjugated
100µg  $605.00

CHMP1A Antibody (HRP) LS-C541460
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
HRP Conjugated
100µl  $755.00

CHMP1A Antibody (Biotin) LS-C521327
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
Biotin Conjugated
100µl  $755.00

CHMP1A Antibody (FITC) LS-C531373
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
FITC Conjugated
100µl  $755.00

CHMP1A Antibody (AP) LS-C503404
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
AP Conjugated
100µl  $755.00

CHMP1A Antibody (APC) LS-C513114
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
APC Conjugated
100µl  $755.00

CHMP1A Antibody (PE) LS-C649570
Rabbit Polyclonal (IgG) to Human CHMP1A
Human
WB
PE Conjugated
100µl  $755.00

CHMP1A Antibody (aa34-61) LS-C168737
Rabbit Polyclonal to Human CHMP1A
Human
WB
Unconjugated
400µl  $305.00
CHMP1A Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The CHMP1A antibody detected the CHMP1A protein (arrow).
CHMP1A Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The CHMP1A antibody detected the CHMP1A protein (arrow).

CHMP1A Antibody LS-C747036
Rabbit Polyclonal (IgG) to Human CHMP1A
Mouse, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of various cell lines, using CHMP1A antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Western blot analysis of extracts of various cell lines, using CHMP1A antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.

CHMP1A Antibody LS-C668184
Rabbit Polyclonal to Human CHMP1A
Human
WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Western blot Image
Western blot Image
Showing 1-25 of 25 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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