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Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Gene Name: | choroideremia-like (Rab escort protein 2) |
Synonyms: | CHML, Rab escort protein 2, REP-2, Choroideraemia-like protein, REP2 |
Target Sequences: | NM_001821 NP_001812.2 P26374 |
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