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CHL1

cell adhesion molecule L1-like

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane.

Gene Name: cell adhesion molecule L1-like
Synonyms: CHL1, CALL, Cell adhesion molecule L1-Like, L1 cell adhesion molecule 2, L1CAM2, Neural cell adhesion molecule, Close homolog of L1
Target Sequences: NM_006614 NP_006605.2 O00533

Publications (1)

1
Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans. Sabrina Simoes, Jessica L Neufeld, Gallen Triana-Baltzer, Setareh Moughadam, Emily I Chen, Milankumar Kothiya, Yasir H Qureshi, Vivek Patel, Lawrence S Honig, Hartmuth Kolb, Scott A Small. Science translational medicine. 2020 November;12: [Full Text Article] [PubMed:33239387] [PMC:PMC7901670] Related Antibodies: LS-C485419.

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Products
Antibodies (10)
Primary (10)
CHL1 (10)
Human (8)
Mouse (5)
Rat (2)
WB (4)
ELISA (8)
IF (1)
Peptide-ELISA (1)
rabbit (8)
mouse (2)
IgG (4)
monoclonal mc (2)
polyclonal pc (8)
05 (1)
Preservative Free (1)
Unconjugated (10)
No (9)
Yes (1)
Select
CHL1 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
20 µl/$256; 100 µl/$412
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CHL1 Antibody - Western blot analysis of extracts of various cells.
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
CHL1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
CHL1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
CHL1 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$256; 100 µl/$412
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).