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CHL1

cell adhesion molecule L1-like

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane.

Gene Name: cell adhesion molecule L1-like
Synonyms: CHL1, CALL, Cell adhesion molecule L1-Like, L1 cell adhesion molecule 2, L1CAM2, Neural cell adhesion molecule, Close homolog of L1
Target Sequences: NM_006614 NP_006605.2 O00533

Publications (1)

1
Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans. Sabrina Simoes, Jessica L Neufeld, Gallen Triana-Baltzer, Setareh Moughadam, Emily I Chen, Milankumar Kothiya, Yasir H Qureshi, Vivek Patel, Lawrence S Honig, Hartmuth Kolb, Scott A Small. Science translational medicine. 2020 November;12: [Full Text Article] [PubMed:33239387] [PMC:PMC7901670] Related Antibodies: LS-C485419.

☰ Filters
Antibodies (10)
ELISA Kits (5)
Proteins (5)
Primary (10)
Recombinant (5)
Sandwich (5)
CHL1 (20)
Human (10)
Mouse (7)
Rat (3)
WB (4)
ELISA (8)
IF (1)
Peptide-ELISA (1)
rabbit (8)
mouse (2)
IgG (4)
monoclonal mc (2)
polyclonal pc (8)
05 (1)
96-Well Strip Plate (5)
Preservative Free (1)
Unconjugated (10)
No (19)
Yes (1)
Cell Culture Supernatants (2)
Cell Lysates (3)
Plasma (4)
Serum (4)
Tissue Homogenates (1)
Fc (1)
GST, N-terminus (1)
His (1)
His,C-terminus (1)
Human (2)
Mouse (3)
HEK 293 Cells (1)
Human Cells (3)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (4)
Select
CHL1 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
20 µl/$256; 100 µl/$412
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CHL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$1,150
CHL1 Antibody - Western blot analysis of extracts of various cells.
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CHL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$1,150
CHL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
CHL1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
CHL1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
CHL1 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$256; 100 µl/$412
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
CHL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
CHL1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CHL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CHL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
113.3 kDa
50 µg/$721
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
113.9 kDa
50 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
120 kDa
50 µg/$721
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
139.4 kDa
50 µg/$721
Viewing 1-20 of 20 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).